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Lower cost laser-based IR chemical imaging microscope

Spero-LT 340

The Spero-LT 340 has been economically configured to get the most out of your research for a lower cost. With all of the same high-performance specifications in speed and resolution as the Spero-QT 340, this is a great solution for tight budgets.

DRS Daylight Solutions

A lower cost alternative to the Spero-QT 340, for laser-based IR chemical imaging

In a class of their own, the Spero® microscopes are the world’s first and only fully integrated, wide-field spectroscopic microscopy and imaging platforms based on our broadly tunable mid-infrared quantum cascade laser technology.

The Spero-LT 340 is the latest model in the Spero product family. The LT offers the same high-performance speed and resolution specifications as the Spero-QT 340 flagship model but is economically configured to address a wide range of materials and life sciences research applications while fitting within tight budget constraints. Contact us to learn what configuration options are available.

Features & Benefits

  • Real-time, high-throughput spectral imaging enabled by ultra-high brightness QCL technology
  • No stains or molecular tags required
  • Label-free IR spectroscopy displays pure chemistry of sample
  • No cryogenic cooling needed
  • Quick setup means more time for analysis


  • Biomedical imaging of tissues, cells, and fluids
  • Cancer research
  • Pharmaceutical testing of tablets, powders, and liquids
  • Drug discovery: API and excipient optimisation and down-selection
  • Protein secondary structure and aggregation testing
  • Real-time reaction monitoring
  • Materials testing and analysis
  • Forensics
  • Chemical detection and identification
Parameter Wide-field IR (0.3 NA)
Wavelength Range: Standard configuration: 1800 cm-1 to 950 cm-1
Other wavelength range options available between 2300 cm-1 and 800 cm-1 Please enquire.
Image Cube Acquisition Time: < 40 s (450 absorbance images collected at 2 cm-1 spacing)
Camera Array Size: 480 x 480
Image Pixel Size: 4.3 μm (0.3 NA)
Diffraction-Limited Spatial Resolution: < 12 μm @ λ = 5.5 μm
Numerical aperture (NA): 0.3
Spectral Resolution: Variable, down to 2 cm-1
Minimum Detectable Signal: < 1 mAU per scan [4]
Working distance (WD): >25 mm
Field of view (FOV): 2 mm x 2 mm (0.3 NA)


Stage Travel X > 75 mm [3]
Stage Travel Y > 50 mm [3]
Stage Travel Z > 10 mm
Stage Repeatability < 1 µm
[1] Reflection mode not included in standard configuration of Spero-LT.
[2] High-Resolution IR Objective and visible objective not included in standard configuration of Spero-LT.
[3] Customisable up to 100 mm
[4] IR imaging mode
Note: Dry gas purge recommended. Please contact us for installation recommendations.


Imaging Modes Spero-LT 340 Spero-QT 340
IR Reflection Yes
IR Transmission Yes Yes
Visible Yes
Mosaic Stitching Yes Yes
Hypercube Collection Yes Yes
High Resolution IR Objective (0.7 NA) Yes
Wide-field IR Objective (0.3 NA) Yes Yes
Spero-QT / Spero-LT Datasheet
Fourier transform vs quantum cascade laser infrared microscopes for histo-pathology. From lab to hospital. (research paper)
High definition infrared chemical imaging of colorectal tissue using a Spero QCL microscope. (research paper)
Real-time mid-IR chemical imaging of dynamic processes. Proton Dueteron exchange within a micro fluidic system using the Spero QCL. (research paper)

Request a Demo

Spero-LT 340

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If you’re interested in the products shown here, or have questions about something you can’t find on our website, please get in touch through the form below.

Our knowledgeable sales team will be happy to help. We can normally source exactly what you need, or work with you to come up with custom solutions.

Alternatively, just call +44 (0) 1933 461 666 and ask to speak to the Photonics team.