Modular, Automated Cellular Imaging Platform
Unbeatable Value In High-Performance Automated Microscope Modules
Zaber Microscope Advantages
Detailed, Unambiguous, and Actionable Images
Capture clear and detailed epifluorescence, brightfield and phase contrast images with a highly light-efficient optical path built around industry-standard Zeiss, Nikon, or Olympus optics.
Rapid Iteration From Research to Production Phases
Modular platform enables OEMs to jumpstart research with a fully functional system and easily interchange modules as needed. System developers have access to Zaber’s catalogue of standard and optional modules. For streamlined integration, these modules share common software tools and both mechanical and electrical interfaces.
Save Money Today and Tomorrow
Low up-front cost delivers exceptional value. Open architecture ensures no hidden long-term costs of expensive proprietary consumables or mandatory software licenses.Deliver Breakthrough Speed
Maximise your throughput with automated multi-channel image acquisition to quickly and accurately scan up to six microplates at once.
Save Space
Minimise your system size to save valuable bench and incubator space.Minimum dimensions: 29 x 29 x 26 cm
Minimum operating footprint for 96 well plate stage: 40 x 35 x 26 cm
Build a Reputation For Reliability
Eliminate in-field failures and deliver products your customers can trust. Zaber’s proven Industrial reliability ensures maximum uptime for years to come.
Motorised Microscope Modules For:
High Content Imaging Systems- Industry standard optics for clear and detailed images
- Rapid illumination channel switching maximises throughput with minimal fluorophore crossover
- High speed Z-stacking for volumetric imaging
- F-Mount camera compatibility for wide area coverage
- High repeatability
Antibody Discovery Systems- High reliability for continuous, high throughput operation
- Optimised for Continuous high-speed operation
- 6 microplate capacity for Long walk-away time
Microfluidics Systems- Ideal for QC and reading of custom microfluidic devices
- Long travel focus stage supports long working distance objectives
- Clearance for manifolds and dispensing systems
- Low latency camera and positioning stage triggering for synchronization with droplet movement
Phenotypic Screening & Confluency Checking Systems- Easy integration into automated cell culture systems
- High speed XY stage with low latency camera triggering maximises throughput
- Rapid LED channel switching minimises fluorophore crossover
Synthetic Biology Systems- Flexible hardware and software platform adapts easily with your design
- Automation to streamline testing
Diagnostic Testing Systems- Stable illumination for reliable quantitative measurements from the first sample, to the last
Drug Discovery Systems- Throughput to rapidly screen large libraries for hit and lead discovery and optimisation
- Optimised for continuous high-speed operation
- 6 microplate capacity for long walk-away time
- Compatible with auto-loading systems
Single Cell & Spatial Biology Systems- Excellent sample positioning stability and repeatability
- Zeiss, Nikon or Olympus optics deliver industry standard imaging performance
- Automated objective changing for coverage of organs, tissues and cellular levels
Live Cell Imaging Systems- Long-term operation in 37 °C incubator
- Compatible with Ibidi, Oko Labs and Tokai Hit stage top incubators
- Highly light efficient optical path for bioluminescence imaging
- Automated loading
Specifications:
| Imaging Modes | Brightfield, Widefield Fluorescence, Darkfeild, Phase Contrast (requires Zeiss phase contrast specific objectives) |
| Objectives | Zeiss ICS, Nikon CF160, Olympus (Evident) |
| Fluorescence Channels | 6 Zeiss “Push & Click” |
| Filter Cube Change Time | 350 ms |
| Filter Position Recognition | Automatic |
| Objective Mounting | Magnetic locking, four objective automated changer single objective manual change |
| Objective Change Time | 1 second |
| Field Number (FN) | 20 mm |
| 96 Well Plate Imaging Time | < 12 seconds |
| Camera Mount | C-Mount, F-Mount available upon request |
| Epi illumination Light Source | 3 Channel LED illuminator |
| Available Wavelengths | 3000K, 385, 473, 568, 625 nm |
| Transmission Illumination Module (optional) | 3000K White LED |
| Transmission Illuminator Working Distance | 72 mm |
| 3d Party Illuminator Support | Optional 3 mm liquid light guide oupler |
| XY Stage Drive Options | Stepper Motor, Linear Motor |
| XY Stage Travel Range | 50 x 50 mm to 305 x 305 mm (Stepper Motor) 130 x 100 mm to 250 x 100 mm (Linear Motor) |
| Maximum XY Stage Speed | 85 mm/sec (Stepper Motor) 750 mm/sec (Linear Motor) |
| XY Stage Repeatability | < 2 µm (Stepper Motor) < 0.5 µm (Linear Motor) |
| Focus Stage | High accuracy Linear Motor |
| Focus Stage Minimum Incremental Move | 20 nm |
| Focus Stage Repeatability | < 200 nm |
| Focus Stage Travel | 25 mm |
| Max. Focus Stage Speed | 800 mm/s |
| Scripting Languages | Python, C++, C#, Java, Java Script, Matlab |
| Supported Software | Inscoper, Microscope-Cockpit, ScanImage, µManager |
| Digital I/O | 1 input, 2 output |
| PC Interface | USB, RS232 Serial |
| Microplate Compatibility | 6, 12, 24 48, 96, 384, 1536 well plates |
| Stage-Top Incubator Compatibility | K-Frame type inserts |
| Dimensions (footprint excluding XY stage) | 29 x 29 x 37 cm |
| Manual Control | 3-Axis, programmable joystick |
| Max. Operating Temperature | 50° C |
| Max. Operating Humidity | 90% Non Condensing |
Frequently Asked Questions:
Our experts will guide you in selecting the correct required and optional modules for your application. We’ll then provide a bespoke quotation based on your selections.
Included
The XY-stage, Z focus stage, motorised filter cube turret, camera tube lens and microscope body are the basic microscope modules which are included with every system.
Optional
Epi and transmitted illuminators, a lighting controller, a junction block for an additional port into the infinity corrected space, a Joystick controller, stage inserts for sample mounting, a motorised objective turret, and cameras are optional and can be ordered if required using the microscope configurator tool. These modules can also be ordered from Zaber individually if you wish to expand your system’s capabilities over time.
While optional, the X-JOY3 joystick controller is highly recommended. It provides simple and intuitive control over sample positioning, focus, filter cube changes and helps make changing objectives even faster.
Not included
Filters, filter cubes, cameras, and objective lenses are not currently included with Zaber microscopes and must be purchased separately. Laser 2000 offers several options, including:
- Semrock’s extensive range of micoscopy filters
- Recommended filter cube: Semrock’s ZHE
- High performance cameras, from Hamamatsu
Sample-specific inserts for the XY stage securely hold the desired sample and ensure its planarity and maintain a consistent focus across the full range of stage travel. Stage inserts for one, two or six microplates are available. Custom inserts are available to meet your application specific requirements.
Stage inserts are XY stage model-specific. The microscope configurator tools display the stage inserts which are supported by your selected XY stage.
X-ADR130 and X-ASR100 stages are compatible with standard “K-Frame” 160 mm x 110 mm inserts and stage top incubators.
Image acquisition is handled in software either by your microscope control software (Inscoper, µManager) or by the software included with your camera.
Zaber Application Notes provide detailed instructions on how to acquire single images or a series of images.
Camera triggering can be done in software using Zaber Motion Library or using IO triggering for high-speed, low-latency synchronisation.
Zaber microscopes support bright field and dark field epi-illumination, widefield and phase contrast transmitted illumination. An optional MLG3A 3 mm liquid light guide coupler is available for use with 3rd party light engines.
While a hardware autofocus module is not available, users can precisely control the focus stage using imaging-based auto-focus methods available in most compatible software. The Zaber Motion Library API provides users with tools required to implement their own solutions. Sample code is available on our GitHub page. Laser-based autofocus implementations are also possible using the optional MJB25 module which provides an additional port into the infinity corrected space.
The Laser 2000 Difference
Response Time Promise:
1 Business Day
Laser 2000’s team of highly responsive and knowledeable Application Engineers are here to help. Contact us for help selecting the right configuration and ensure your experiments are running smoothly. We’ll get back to you in 1 business day.
30-Day Risk-Free Trial
Rapid turn-around customisations give you the freedom to upgrade, adapt and optimise your system in ways not possible with traditional research microscopes.Quick Customisation
Minimise your system size to save valuable bench and incubator space.Minimum dimensions: 29 x 29 x 26 cm
Minimum operating footprint for 96 well plate stage: 40 x 35 x 26 cm
